Thomas Record

Research Website

Biophysical Thermodynamics, Kinetics

• Kinetics and mechanism of function of RNA polymerase as a molecular machine in transcription initiation

• Conformational changes in transition states and intermediates of protein and nucleic acid processes using solute and salt effects on rate constants.

• Thermodynamics and mechanism of protein folding, nucleic acid helix formation

• Free energies of hydrogen bonding, hydrophobic and other interactions of C, N, O unified atoms of amides and proteins in water from measurements of small solute interactions

Also Professor of Biochemistry